Table 1.
Baseline characteristics
| Non‐MetS group n = 135 | Newly‐MetS group n = 75 | P | |
|---|---|---|---|
| Male, n (%) | 47 (34.8) | 41 (54.7) | 0.005 |
| Age (years) | 49.52 ± 6.6 | 50.9 ± 6.4 | 0.140 |
| BMI (kg/m2) | 23.2 ± 2.8 | 25.7 ± 2.5 | <0.001 |
| WC (cm) | 80.2 ± 8.3 | 87.9 ± 7.5 | <0.001 |
| FPG (mmol/L) | 5.2 (4.9–5.7) | 5.3 (5.1–5.6) | 0.084 |
| 2hPG (mmol/L) | 6.7 (5.7–7.8) | 7.1 (6.0–8.7) | 0.061 |
| FINS (IU/L) | 14.2 (11.1–18.5) | 15.9 (12.5–21.4) | 0.014 |
| HOMA‐β | 165.00 (110.31–213.90) | 161.56 (128.55–243.56) | 0.197 |
| HOMA‐IR | 3.48 (2.53–4.59) | 3.91 (3.09–5.16) | 0.017 |
| HbA1c (%) | 5.8 (5.4–6.1) | 6.0 (5.5–6.2) | 0.334 |
| TC (mmol/L) | 4.9 (4.3–5.5) | 5.2 (4.5–5.8) | 0.098 |
| TG (mmol/L) | 1.2 (0.9–1.5) | 1.5 (1.1–1.9) | <0.001 |
| HDL (mmol/L) | 1.5 (1.3–1.7) | 1.3 (1.1–1.5) | 0.003 |
| LDL (mmol/L) | 3.0 (2.5–3.6) | 3.3 (2.7– 3.9) | 0.009 |
| SBP (mmHg) | 117 ± 13 | 124 ± 11 | <0.001 |
| DBP (mmHg) | 75 ± 8 | 80 ± 8 | <0.001 |
| HR (/min) | 79 ± 9 | 78 ± 10 | 0.840 |
| BUN (mmol/L) | 5.16 ± 1.25 | 5.39 ± 1.38 | 0.232 |
| Cr (μmol/L) | 59.96 ± 11.89 | 66.12 ± 14.31 | 0.002 |
| UA (μmol/L) | 271 ± 81 | 332 ± 79 | <0.001 |
| ALT (IU/L) | 16 (11–20) | 22 (15–32) | <0.001 |
| AST (IU/L) | 19 (17–22) | 23 (18–28) | <0.001 |
| GGT (IU/L) | 18 (14–25) | 28 (19–57) | <0.001 |
| Smoke, n (%) | 33 (24.4) | 31 (41.3) | 0.011 |
| Drink, n (%) | 20 (14.8) | 14 (18.7) | 0.468 |
| FAM3B (ng/mL) | 21.85 (19.38–24.17) | 28.56 (25.32–38.10) | <0.001 |
Data presented as mean ± standard deviation or median (quartile), unless otherwise stated. 2hPG, 2‐h plasma glucose; ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BUN, blood urea nitrogen; Cr, serum creatinine; DBP, diastolic blood pressure; FAM3B, member B of the family with sequence similarity 3; FINS, fasting plasma insulin; FPG, fasting plasma glucose; GGT, gamma glutamyl transpeptidase; HbA1c, glycated hemoglobin; HDL, high‐density lipoprotein cholesterol; HOMA‐β, homeostasis model assessment of β‐cell function; HOMA‐IR, homeostasis model assessment of insulin resistance; HR, heart rate; LDL, low‐density lipoprotein cholesterol; MetS, metabolic syndrome; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride; UA, uric acid; WC, waist circumference.