Table 1. Clinical characteristics, laboratory findings, treatment, and outcome of patients with CMV colitis during dasatinib treatment.
[Ref]/ Patient | Age/Sex | Hematologic disease | Dasatinib duration | Lymphocyte | Coinfection pathogen | Serum CMV DNA titer (copies/ml) | Dasatinib during treatment | Treatment | Dasatinib after antiviral treatment | Relapse | |
---|---|---|---|---|---|---|---|---|---|---|---|
[8] | F/39 | CML, CP | 30 month | Not mentioned | None | Not mentioned | Stop | Ganciclovir for 6 weeks | Restart | None | |
1 | M/67 | CML, CP | 14 month | 1,744/mm3 | None | 760 | Stop | Ganciclovir for 19 days | Restart | None | |
2 | F/43 | CML, CP | 2 month | 1,115/mm3 | Clostridium difficile | 1,650 | Stop | Ganciclovir for 12 days | Restart | None | |
3 | M/51 | CML, CP | 14 month | 1st episode | 4,928/mm3 | None | unchecked | Continued | None | Continued | Relapsed after 6 weeks |
2nd episode | 4,190/mm3 | None | unchecked | Continued | Valganciclovir for 21 day | Continued | None | ||||
4 | M/54 | Ph (+) ALL | 3 month | 1st episode | 300/mm3 | None | unchecked | Continued | None | Continued | relapsed after 2 weeks |
2nd episode | 1,398/mm3 | Clostridium difficile | 925 | Stop | Ganciclovir for 19 days | Restart | None | ||||
5 | F/55 | Ph (+) ALL | 5 month | 251/mm3 | None | 2500 | Continued | Ganciclovir for 10 days | Stop | None |
CMV, cytomegalovirus; F, female; CML, chronic myeloid leukemia; CP, chronic phase; M, male; Ph (+) ALL, Philadelphia chromosome-positive acute lymphoblastic leukemia.
Case of reference 9 was not included in the table because only abstract written in English was available.