Table 1.
Genotype distributions and associations of CTLA-4 +49 G/A and CT60 SNPs with T1D risk in Chinese Han population.
| SNP | pos (hg38) | Ref/Alt | Genotype distribution | MAF | Additive | Dominant | Recessive | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T1D | Controls | T1D | Controls | OR (95%CI) | P value | OR (95%CI) | P value | OR (95%CI) | P value | |||
| +49 G/A | 203867991 | A§/G | 73/403/529 | 268/1086/1178 | 0.273 | 0.320 | 1.25 (1.11–1.41) | 2.82E-04*** | 0.78 (0.68–0.91) | 1.58E-03** | 1.28 (1.10–1.48) | 8.60E-04*** |
| CT60 | 203874196 | G/A§ | 729/248/28 | 1725/749/100 | 0.151 | 0.184 | 0.79 (0.68–0.91) | 1.09 E-03** | 1.41 (0.92–2.16) | 0.114 | 0.77 (0.65–0.90) | 1.02 E-03** |
Note: §MAF, minor allele frequency. **P < 0.01 or ***P < 0.001.