Table 7. ISHLT standardized cardiac biopsy grading: ACR⁷⁰⁾ .

Grade	Description	Prior classification
0R	No rejection	0
1R, mild	Interstitial and/or perivascular infiltrate with up to one focus of myocyte damage	1A, 1B, 2
2R, moderate	Two or more foci of infiltrate with associated myocyte damage	3A
3R, severe	Diffuse infiltrate with multifocal myocyte damage ± edema ± hemorrhage ± vasculitis	3B, 4

ACR = acute cellular rejection; ISHLT = International Society for Heart and Lung Transplantation; R = revised.