Table 5.
Up-Regulated Genes According to the Clinical Parameters of Oral Tumors
| Genes | Expression pattern in OSCCa | Tumor extent | P-value | TNM stage | P-value | ||
|---|---|---|---|---|---|---|---|
| T1-T2 | T3-T4 | I-II | III-IV | ||||
| Fold change (median)a | Fold change (median) | Fold change (median) | Fold change (median) | ||||
| ATOX1 | Up-regulated | 1.425 | 5.010 | 0.229 | 1.294 | 3.989 | 0.114 |
| PRDX4 | Up-regulated | 1.376 | 2.548 | 0.237 | 1.243 | 2.166 | 0.100 |
| PRNP | Up-regulated | 2.961 | 2.244 | 0.629 | 2.744 | 2.711 | 0.857 |
| SOD2 | Up-regulated | 1.663 | 2.344 | 0.886 | 1.806 | 1.790 | 1.0 |
OSCC, oral squamous cell carcinoma;
a
, Compared to non-tumor tissue.