Table 2.
Allelic Frequencies and Genotype Distribution of the Studied SNPs of NR3C1 (GR) in ALL Children (n=70) and Control Subjects (n=60).
| SNP | NR3C1 GENE | OR (95%Cl) | P value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Allelic Frequency | OR (95%Cl) | P value | Genotype | |||||||
| WT | MUT | WT | HET | MUT | ||||||
| ER22/23EK | Case | 140 (100%) | 0 (0%) | 0.286 (0.049-1.666) | 0.16 | 70 (100%) | 0 (0%) | 0% | ||
| Control | 116 (96.66%) | 4 (3.33%) | 56 (93.33%) | 4 (6.66%) | 0% | |||||
| BclI | Case | 91 (65%) | 49 (35%) | 0.367 (0.129-1.047 | 0.064 | 32 (45.7%) | 27 (38.57% | 11 (15.71%) | 1.886 (0.694-5.122) | 0.285 |
| Control | 79 (65.83%) | 41 (34.16%) | 24 (40%) | 31 (51.66%) | 5(8.33%) | |||||
| N363S | Case | 135 (96.4%) | 1 (3.6%) | 0.429 (0.027-6.739) | 0.511 | 65 (92.8%) | 5 (7.2%) | 0 | ||
| Control | 118 (98.3%) | 2 (1.7%) | 58 (97%) | 2 (3%) | 0 | |||||