Table 3.

Genotype (Wild vs.Hetero+Mutated) in ALL Children (n=70) with Liver Toxicity induced by Glucocorticoid Therapy

SNP	Liver toxicity in wild type	Liver toxicity in SNP carrier	P Value (0.05)	OR* (95% CI)
ER22/23K	50.70%	0.00%	1	0.971 (0.918-1.028)
BclI	46.90%	83.30%	0.198	2.667 (0.526-7.330)
N363S	47.70%	40%	0.356	1.097 (0.961-1.251)

^*patients with liver toxicity versus total number of patients