Table 4.
Odds Ratios and 95% Confidence Intervals for the Association between DII and Breast Cancer in an Iranian Case-control Study, 2015-2016 (n=298)
| Dietary Inflammatory Index (Tertiles) OR (95% CI) | Ptrend-valuea | DII (Continuous)bOR (95% CI) | P-Value | |||
|---|---|---|---|---|---|---|
| DII | Tertile 1 ≤ -0.46 | Tertile 2-0.45 to +0.95 | Tertile 3>+0.95 | |||
| HER 2 receptor +ve cases (61/148) | 1 (ref.) | 3.27 (0.96, 11.07) | 17.42 (4.84, 62.71) | <0.0001 | 2.52 (1.73, 3.67) | <0.0001 |
| Progesterone receptor +ve cases (89/148) | 1 (ref.) | 2.54 (0.98, 6.60) | 7.86 (2.87, 21.53) | <0.0001 | 1.87 (1.41, 2.48) | <0.0001 |
| Estrogen receptor +ve cases (105/148) | 1 (ref.) | 2.67 (1.09, 6.52) | 8.16 (3.14, 21.19) | <0.0001 | 1.86 (1.43, 2.43) | <0.0001 |
| Lymph node invasive case (56/148) | 1 (ref.) | 6.61 (1.63, 26.77) | 43.36 (9.42, 199.55) | <0.0001 | 3.89 (2.36, 6.42) | <0.0001 |
a
P-value for trend derived using the median approach;
b
One unit increase corresponding to ≈34% of its range in the current study;
cAdjusted for age, energy, education, exercise (Mets hr/week), BMI, smoking, family history of cancer, age at menarche, parity, marital status, menopausal status, oral contraceptive use and hormone replacement therapy.