Skip to main content
. 2018 Jun 5;5:714–722. doi: 10.1016/j.toxrep.2018.05.014

Table 4.

Biochemical results in 7 and 21 days old pups lung tissues.

Control
TS
TS + ALA
ALA
Age (days) 7 21 7 21 7 21 7 21
Apoptotic index (%) 2,92 ± 1.82 3,01 ± 1.78 35,50 ± 6.11a 30,07 ± 6.84a 14,05 ± 1.54ab 12,54 ± 2.43ab 4,05 ± 0.89b 4,25 ± 1.48b
Caspase-3 immunreactivity 0,35 ± 0.15 0,2 ± 0.13 2,30 ± 0.48a 2,1 ± 0.6a 1,04 ± 0.39 ab 0,81 ± 0.2 ab 0,52 ± 0.23b 0,4 ± 0.15 b
SP-A immunreactivity 1,43 ± 0.17 2,00 ± 0.24 0,22 ± 0.08a 0,43 ± 0.08a 1,03 ± 0.18 b 1,30 ± 0.10ab 1,13 ± 0.16b 1,85 ± 0.19b
mRNA level (fold change) 1 1 0,114 ± 0.09a 0,594 ± 0.03a 2,495 ± 0.02ab 2,603 ± 0.23ab 3,173 ± 0.01ab 3,427 ± 0.14ab
VEGF immunreactivity 1,23 ± 0.13 2,00 ± 0.24 0,43 ± 0.05a 0,51 ± 0.11a 0,91 ± 0.21 b 1,45 ± 0.16 b 1,16 ± 0.14b 1,75 ± 0.32b
mRNA level (fold change) 1 1 0,131 ± 0.03a 0,327 ± 0.12a 2,173 ± 0.11ab 2,561 ± 0.01ab 5,189 ± 0.32ab 5,971 ± 0.26ab