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. Author manuscript; available in PMC: 2018 Jul 5.
Published in final edited form as: Bioorg Med Chem. 2010 Apr 21;18(14):5449–5456. doi: 10.1016/j.bmc.2010.04.050

Figure 3.

Figure 3

A) Structure of the rationally designed azaindole (IK04). B) The 5 inhibitors of both HCPTP isoforms identified as having IC50 values less than 100 μM at both pH 5 and 7: 30080, 45576, 114792, 128437, and 643735. C) The structures of the additional 6 active inhibitors of HCPTP-A at pH 7: 49848, 65763, 85359, 141566, 210786, and 319095. Compound 45576, which has been determined not to cause aggregation of HCPTP, is boxed for additional emphasis.