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Effect of pretreatment with FK‐888 (0.1 nmol·mL−1; i.c.v., n = 9 and 1.0 nmol·mL−1, n = 5) on DPCPX‐enhanced citric acid‐induced cough (A), changes in Penh (B) and Penh AUC (C). Values represent means + SEM. * P < 0.05, significant difference compared with vehicle alone (n = 13) and FK‐888 alone (n = 4)‐treated animals. # P < 0.05, significant difference compared with DPCPX (3.3 nmol·mL−1)‐treated animals.
