Fig. 8.

ErbB4 deletion increased G2/M arrest after UUO injury. A: representative images from sham-operated kidneys in either group (n = 6) and 3 and 6 days post-UUO kidneys from wild-type (n = 6) and ErbB4^−/−ht⁺ mice (n = 8) stained with Ki-67 (red), p-Histone H3 (green), and DAPI (blue). Scale bar, 50 µm. B: p-Histone H3 and Ki-67-positive cells were counted using ImageJ software from at least 20 random fields. p-Histone H3-to-Ki-67 ratio was used to evaluate cells in G2/M phase. Values represent means ± SE. *P < 0.05 compared with the wild type at the same time point.