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. 2017 May 17;314(5):F702–F714. doi: 10.1152/ajprenal.00044.2017

Fig. 5.

Fig. 5.

Iron chelation increases cell viability in erastin-treated cells. Cell viability in HO-1+/+ (A) and HO-1−/− (B) PTCs treated with either 0.1 or 1 μM erastin with or without 0.1 mM DFO for 16 h. C: representative Western blot showing HO-1 protein levels in HO-1+/+ PTCs treated with erastin in the presence or absence of DFO for 16 h. Data represented as means ± SE of three independent experiments with six to eight replicates in each experiment; **P < 0.01 compared with vehicle-treated cells; #P < 0.01 compared with 1 μM erastin-treated cells (HO-1+/+ or HO-1−/−).