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. 2017 May 17;314(5):F702–F714. doi: 10.1152/ajprenal.00044.2017

Fig. 7.

Fig. 7.

Iron supplementation and/or HO-1 deficiency potentiate erastin-induced ferroptosis. Cell viability in HO-1+/+ (A) and HO-1−/− (B) PTCs treated with either 0.1 or 1 μM erastin with or without 10 μg/ml FAC (ferric ammonium citrate) for 16 h compared with vehicle-treated cells. Data represented as means ± SE of four to six independent experiments with three to eight replicates in each experiment; **P < 0.01 compared with vehicle-treated PTCs; #P < 0.01 compared with 0.1 or 1 μM erastin-treated cells.