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. 2017 May 17;314(5):F702–F714. doi: 10.1152/ajprenal.00044.2017

Fig. 9.

Fig. 9.

Glutathione supplementation rescues renal epithelial cells from erastin-induced ferroptosis. Cell viability of HO-1+/+ (A) and HO-1−/− (B) PTCs treated with either 0.1 or 1 μM erastin with or without 0.5 or 1 mM NAC for 16 h (magnification ×10). C: representative Western blot showing protein levels of HO-1+/+ PTCs treated with either 0.1 or 1 μM erastin with or without NAC cotreatment. Data represented as means ± SE of three or four independent experiments with four to eight replicates in each experiment; *P < 0.05 and **P < 0.01 compared with vehicle-treated cells; #P < 0.01 compared with erastin-only treatments.