Figure 1.

Effects of Salmonella (S.C.) on cellular migration in B16F10 and LL2 cells. B16F10 cells and LL2 cells (2 × 10⁵ cells/well) were placed onto plates and incubated at 37 °C for 24 h. The cells cocultured with Salmonella (Multiplicity Of Infection (MOI) = 10) for 4 h. The migration distances of different groups of B16F10 and LL2 cells were shown (a) and measured (b) (×400); (c) Tumor cells were placed on the upper layer of a cell culture insert with permeable membrane and then treated with Salmonella (MOI = 10) for 4 h. Following an incubation 24 h, the cells migrated through the membrane were stained with 4′,6-Diamidino-2-Phenylindole (DAPI) and counted under a fluorescence microscope (×400).