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. 2018 Feb 8;314(6):L967–L983. doi: 10.1152/ajplung.00553.2017

Table 1.

List of CYPs associated with different drugs known to produce D-PAH

Drugs Cytochromes
Monocrotaline Cyt3A4
Fenfluramine Cyt1B1
Metamphetamine Cyt 3A4, 2D6
Dasatinib Cyt 3A4, 1A1,1B1
Interferon Cyt 3A4, 1A2
Sugen 5416 Cyt 1A1, 1B1
Trichloroethylene Cyt 4A10
Cigarette smoke components Cyt 1A1, 2A6, 2E1, 3A

CYP, cytochrome P-450; D-PAH, drug-induced pulmonary arterial hypertension.