Table 1.
Body characteristics of young and old male Fischer-344 rats
| Young |
Old |
|||
|---|---|---|---|---|
| CON | PTH | CON | PTH | |
| ACh | ||||
| Body mass, g | 361 ± 8 (n = 13) | 369 ± 4 (n = 15) | 449 ± 9a (n = 12) | 439 ± 12a (n = 14) |
| Marrow mass, mg | 52 ± 8 (n = 17) | 53 ± 6 (n = 14) | 93 ± 23 (n = 10) | 91 ± 20 (n = 13) |
| Diethylamine NONOate | ||||
| Body mass, g | 361 ± 11 (n = 8) | 364 ± 5 (n = 10) | 448 ± 12a (n = 8) | 427 ± 14a (n = 7) |
| Marrow mass, mg | 47 ± 12 (n = 7) | 57 ± 7 (n = 7) | 93 ± 40 (n = 6) | 108 ± 37 (n = 7) |
| Blood chemistry | ||||
| Plasma PTH, pg/ml | 6.12 ± 0.05 (n = 5) | 5.70 ± 0.05b (n = 5) | 5.95 ± 0.07 (n = 8) | 4.67 ± 0.08b (n = 8) |
| Plasma Ca2+, mg/dl | 12.6 ± 0.5 (n = 7) | 12.4 ± 0.3 (n = 9) | 14.3 ± 0.6c (n = 5) | 12.4 ± 0.6 (n = 7) |
Values are means ± SE; the sample size n represents the number of rats per group. CON, control; PTH, parathyroid hormone.
a
P < 0.050 vs. Young CON and Young PTH.
b
P < 0.050 vs. all other groups.
c
P = 0.070 vs. all other groups.