Table 3.
Maximal diameter, percent spontaneous tone, and EC50 of the femoral principal nutrient artery following the ACh dose-response experiment in young and old CON and PTH-treated rats in the absence and presence of marrow
| CON | CON+Marrow | PTH | PTH+Marrow | |
|---|---|---|---|---|
| Young | ||||
| Maximal diameter, µm | 188 ± 11 (n = 14) | 187 ± 9 (n = 18) | 198 ± 8 (n = 15) | 190 ± 7 (n = 14) |
| Spontaneous tone, % | 27 ± 4 (n = 14) | 34 ± 4 (n = 16) | 36 ± 4 (n = 14) | 29 ± 5 (n = 8) |
| EC50 | 7.48 × 10−7 ± 2.56 × 10−7(n = 14) | 1.09 × 10−6 ± 3.74 × 10−7(n = 13) | 4.60 × 10−7 ± 1.85 × 10−7(n = 12) | 8.75 × 10−7 ± 4.54 × 10−7(n = 7) |
| Old | ||||
| Maximal diameter, µm | 196 ± 12 (n = 12) | 196 ± 16 (n = 10) | 210 ± 8 (n = 13) | 224 ± 8 (n = 11) |
| Spontaneous tone, % | 37 ± 5 (n = 12) | 28 ± 2 (n = 10) | 33 ± 2 (n = 14) | 32 ± 3 (n = 13) |
| EC50 | 1.98 × 10−7 ± 1.13 × 10−7(n = 12) | 6.36 × 10−6 ± 4.66 × 10−6(n = 10) | 2.98 × 10−7 ± 1.30 × 10−7(n = 13) | 1.88 × 10−6 ± 1.04 × 10−6(n = 11) |
Values are means ± SE; the sample size n represents the number of rats per group. CON, control; PTH, parathyroid hormone.