Table 4.
Maximal diameter, percent spontaneous tone, and EC50 of the femoral principal nutrient artery following the diethylamine NONOate dose-response experiment in young and old CON and PTH-treated rats in the absence and presence of marrow
| CON | CON+Marrow | PTH | PTH+Marrow | |
|---|---|---|---|---|
| Young | ||||
| Maximal diameter, µm | 210 ± 11 (n = 8) | 206 ± 8 (n = 11) | 197 ± 13 (n = 8) | 197 ± 9 (n = 8) |
| Spontaneous tone, % | 36 ± 6 (n = 8) | 36 ± 5 (n = 11) | 29 ± 2 (n = 10) | 34 ± 10 (n = 8) |
| EC50 | 6.21 × 10−6 ± 4.89 × 10−6(n = 8) | 6.44 × 10−5 ± 5.75 × 10−5(n = 11) | 3.31 × 10−6 ± 2.70 × 10−6(n = 8) | 5.39 × 10−6 ± 3.96 × 10−6(n = 8) |
| Old | ||||
| Maximal diameter, µm | 215 ± 10 (n = 7) | 211 ± 26 (n = 7) | 201 ± 13 (n = 8) | 217 ± 10 (n = 8) |
| Spontaneous tone, % | 34 ± 4 (n = 7) | 28 ± 8 (n = 6) | 34 ± 6 (n = 8) | 37 ± 6 (n = 9) |
| EC50 | 4.97 × 10−6 ± 4.45 × 10−6(n = 7) | 3.16 × 10−6 ± 2.15 × 10−6(n = 7) | 1.59 × 10−6 ± 1.38 × 10−6(n = 8) | 2.21 × 10−7 ± 1.20 × 10−7(n = 8) |
Values are means ± SE; the sample size n represents the number of rats per group. CON, control; PTH, parathyroid hormone.