Figure 2.

Effect of DS on irradiation-induced epithelial junctions. The relative number of adherens junction marker β-catenin and e-cadherin- (a–h) or tight junction marker claudin-1 and occludin positive epithelial cells (i–p) and their respective staining intensity were analyzed, in the germinal and functional compartments, respectively. Data points represent the mean of 5 animals, error bars indicate ±1 SD. The shaded areas illustrate the mean (±1 SD) from 5 control animals. The fractionation protocol is indicated on top of the abscissae. Histophotographs illustrate representative junction marker staining in on day 0 and after irradiation without and with DS on day 14 of the study period. * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, Scale bar = 20 µm.