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. 2018 May 25;19(6):1572. doi: 10.3390/ijms19061572

Figure 1.

Figure 1

(A) Representative Western blot analysis of SIRT1 expression in fibroblasts from controls and psoriatic patients. Histogram represents data from controls (n = 4 biopsies) and patients (n = 4 biopsies); (B) SIRT1 activity in fibroblasts from controls (n = 4 biopsies) and psoriatic patients (n = 4 biopsies); (C) SIRT1 activity in fibroblasts from lesional psoriatic skin (n = 4 biopsies) after 24 h of incubation with different concentrations of SRT1720. Each experiment was performed in triplicate. * Significant difference (p ≤ 0.05) vs. fibroblasts from healthy patients. # Significant difference (p ≤ 0.01) vs. PSO fibroblasts.