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. 2018 Jun 1;19(6):1644. doi: 10.3390/ijms19061644

Figure 6.

Figure 6

Effect of PL on neuronal cell loss in Aβ25–35 plaque-injected mice. After stereotaxic injection of Aβ25–35 plaque, mice were treated with vehicle, PL, or donepezil for 17 days. Neuronal cells were stained with anti-NeuN antibody. The optical density of the NeuN-stained cells was measured in the (A) CA3 and (B) DG; (C) Representative images of NeuN-positive neurons in the CA3 (up) and DG (down) of mice brain. Scale bar = 30 μm. Values are mean ± standard error of the mean. *** p < 0.001 vs. sham group; # p < 0.05 and ## p < 0.01 vs. Aβ25–35 plaque group. Donepezil was used as a positive control.