Table 1.
Patients’ symptomology and clinical characteristics
| Patient ID | Age at Implant, yr/Sex | Location (Type) of Stroke | Time from Stroke to Baseline, yr | Pain Lateralization | Mean Pain Rating at Enrollment (1–10) | Sensory Deficit in Painful Zone |
|---|---|---|---|---|---|---|
| 01 | 50 (M) | Left thalamus (I) | 3 | Right | 7 | Severe |
| 02 | 49 (M) | Right Medulla (I) | 9 | Left | 6 | Severe |
| 03 | 48 (F) | Left basal ganglia (H) | 9 | Right | 9 | Severe |
| 05 | 53 (M) | Left thalamus (H) | 3 | Right | 7 | Severe |
| 06 | 56 (M) | Right thalamus (H) | 1 | Left | 10 | Moderate |
| 07 | 49 (M) | Left brain stem (H) | 1 | Right | 9 | Severe |
| 08 | 51 (M) | Left temporal stem (H) | 2 | Right | 10 | Severe |
| 09 | 43 (F) | Left thalamus (H) | 4 | Right | 9 | Severe |
| 10 | 59 (F) | Right middle cerebral artery (I) | 9 | Left | 10 | Severe |
| 11 | 60 (F) | Right basal ganglia (H) | 6 | Left | 8 | Severe |
Subject 01 dropped out of the study after enrollment, and subjects 03 and 10 were eliminated from data analysis due to lack of attention to experimental procedures. Subjects 02, 06, 08, 10, and 11 (bold type) were classified as responders on the basis of clinical outcome. M, male, F, Female, I, ischemic stroke; H, hemorrhagic stroke. Pain duration was the same as “Time from stroke to baseline” in all patients. Sensory deficits were defined as follows: mild, subjective mild hypoesthesia but able to distinguish sharp from dull; moderate, inability to consistently distinguish between sharp and dull; and severe, anesthesia dolorosa.