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Effects of PI3K inhibitor and ROCK inhibitor on stiffness of MCF-10A, PTEN−/−, 10A-KRAS(G12V), and PTEN−/−KRAS(G12V) cells. Cells are seeded on collagen-coated substrates and treated with 20 µM LY294002 or 10 µM Y27632. Cell stiffness is normalized to the untreated cell stiffness of the same cell type. Number of cells measured: n = 14–33.
