Table 2.

The effect of nevirapine on the binding of ligand peptides to HLA-DR molecules.

HLA Allele		DRB1*01:01	DRB1*07:01	DRB1*15:01
Concentration of nevirapine (μM)	1000	263.9 ± 15.5 #	62.6 ± 3.9	101.3 ± 14.9
	200	99.7 ± 11.3	110.4 ± 5.5	94.6 ± 10.6
	40	106.2 ± 6.5	76.9 ± 4.6	93 ± 10.4
	8	101.9 ± 8.1	132.2 ± 64	98.9 ± 3.4

The effects of nevirapine on the binding of ligand peptides to three HLA-DRs are expressed as % binding of ligand peptides in the presence of nevirapine to that in dimethyl sulfoxide (DMSO) control (n = 8). Values represent the mean ± SD of quadruplicate. ^# p < 0.001, compared with the DMSO control.