DEA |
Drug Enforcement Administration |
FM |
fibromyalgia |
SLC6A4 |
serotonin transporter gene |
TRPV2 |
transient receptor potential vanilloid 2 genes |
CSF |
cerebrospinal fluid |
(5-HT) |
5-hydroxytriptamine |
(5-HTT) |
serotonin transporter |
COMT |
Catechol-O-methyltransferase |
SNP |
short nucleotide polymorphisms |
DRD4 |
dopamine receptor D4 |
MAO |
A-monoamine oxidase |
GTPCH |
guanosine triphosphate cyclohydrolase |
GABRB3 |
GABA receptor beta 3 subunit |
APOE |
apolipoprotein MYT1L myelin transcription factor 1 |
CLBP |
chronic low back pain |
OPRM1 |
opioid receptor µ 1 |
LDD |
lumbar disk disease |
GDF5 |
growth differentiation factor 5 |
COMT |
catecholaminergic enzyme |
VNTR |
variable nucleotide tandem repeat |
NSAIDs |
(nonsteroidal anti-inflammatory drugs) |
ACAN |
chondroitin sulfate-1 encoding domain of the aggrecan gene |
EDNRA |
encoding endothelin type A receptor |
MTHFR |
encoding methylenetetrahydrofolate reductase |
NOS3 |
encoding endothelial nitric oxide synthase |
ACE |
encoding angiotensin-1 converting enzyme |
TGFB2 |
encoding β-2 transforming growth factor |
TGFBR2 |
encoding β-2 transforming growth factor receptor |
VEGF |
vascular endothelial growth factor |
NOTCH3 |
neurogenic locus notch homolog protein 3 |
ESR1 |
estrogen receptor 1 |
MTHFR |
methylenetetrahydrofolate reductase |
DPN |
painful diabetic peripheral neuropathy |
5-HTTLPR |
5-hydroxytriptamine transporter-linked polymorphic region |
TN |
trigeminal neuralgia |
CYP450 |
cytochrome P450 |
TCA |
tricyclic antidepressant |
DPWG |
Dutch Pharmacogenetics Working Group |
CPIC |
Clinical Pharmacogenetics Implementation Consortium |
SSRIs |
selective serotonin reuptake inhibitors |
NSRIs |
non-selective reuptake inhibitors |
IM |
intermediate-metabolizer |
EM |
extensive metabolizer |
DDIs |
drug-drug interactions |
DGIs |
drug-gene interactions |
DDGIs |
drug-drug-gene interactions |
DOA |
deceased patients with opioid addiction |
LOA |
living patients with opioid addiction |
ABCB1 |
ATP-binding cassette sub-family B member 1 |