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. 2018 Jun 8;19(6):1707. doi: 10.3390/ijms19061707
DEA Drug Enforcement Administration
FM fibromyalgia
SLC6A4 serotonin transporter gene
TRPV2 transient receptor potential vanilloid 2 genes
CSF cerebrospinal fluid
(5-HT) 5-hydroxytriptamine
(5-HTT) serotonin transporter
COMT Catechol-O-methyltransferase
SNP short nucleotide polymorphisms
DRD4 dopamine receptor D4
MAO A-monoamine oxidase
GTPCH guanosine triphosphate cyclohydrolase
GABRB3 GABA receptor beta 3 subunit
APOE apolipoprotein MYT1L myelin transcription factor 1
CLBP chronic low back pain
OPRM1 opioid receptor µ 1
LDD lumbar disk disease
GDF5 growth differentiation factor 5
COMT catecholaminergic enzyme
VNTR variable nucleotide tandem repeat
NSAIDs (nonsteroidal anti-inflammatory drugs)
ACAN chondroitin sulfate-1 encoding domain of the aggrecan gene
EDNRA encoding endothelin type A receptor
MTHFR encoding methylenetetrahydrofolate reductase
NOS3 encoding endothelial nitric oxide synthase
ACE encoding angiotensin-1 converting enzyme
TGFB2 encoding β-2 transforming growth factor
TGFBR2 encoding β-2 transforming growth factor receptor
VEGF vascular endothelial growth factor
NOTCH3 neurogenic locus notch homolog protein 3
ESR1 estrogen receptor 1
MTHFR methylenetetrahydrofolate reductase
DPN painful diabetic peripheral neuropathy
5-HTTLPR 5-hydroxytriptamine transporter-linked polymorphic region
TN trigeminal neuralgia
CYP450 cytochrome P450
TCA tricyclic antidepressant
DPWG Dutch Pharmacogenetics Working Group
CPIC Clinical Pharmacogenetics Implementation Consortium
SSRIs selective serotonin reuptake inhibitors
NSRIs non-selective reuptake inhibitors
IM intermediate-metabolizer
EM extensive metabolizer
DDIs drug-drug interactions
DGIs drug-gene interactions
DDGIs drug-drug-gene interactions
DOA deceased patients with opioid addiction
LOA living patients with opioid addiction
ABCB1 ATP-binding cassette sub-family B member 1