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(A) NTD handshake dimerization mode and (B) details about the interactions stabilizing this configuration. The two NTDs are shown in blue and red cartoons and the residues important for the dimerization in green sticks. (C) Ni2+ mediated multimerization (in this case the different NTDs are depicted in green, violet, yellow and sandy and (D) details about the Ni2+ coordination. Structures extracted from the PDB entry 4ZIA [27].
