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. 2018 May 31;19(6):1633. doi: 10.3390/ijms19061633

Scheme 1.

Scheme 1

The Y-scaffold (red line) and linear linker (yellow line) were designed to form a DNA hydrogel by hybridization of the reactive ends. The ATP aptamer sequence (green line) was inserted into the region of the linker. On addition of adenosine triphosphate (blue star), the conformational transition of the aptamer had a great influence on the mechanical properties of the DNA hydrogel.