AF-1, AF-2 |
Activation function 1, 2 |
CAR |
Constitutive androstane receptor |
CCRP |
Cytoplasmic CAR retention protein |
CYP |
Cytochrome P450 |
CYP3A4 |
Cytochrome P450 3A4 |
DBD |
DNA-binding domain |
DDI |
Drug-drug interaction |
GR |
Glucocorticoid receptor |
Hsp90 |
Heat shock protein 90 |
LBD |
Ligand binding domain |
NR |
Nuclear receptor |
ODE |
Ordinary differential equation |
PDE |
Partial differential equation |
PK/PD |
Pharmacokinetic/pharmacodynamic |
PAK |
Protein kinase A |
PXR |
Pregnane X receptor |
RXRα |
Retinoid X receptor-α |
SRC |
Steroid receptor coactivator |
TAT |
Tyrosine aminotransferase |
VDR |
Vitamin D receptor |
XREM |
Xenobiotic responsive enhancer module |