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Molecular and pathological features of gastric cancer and adenoma in Lynch syndrome and FAP.
| Mutated Gene | Mutation | Age at Onset | Gender | Histology | Stage |
|---|---|---|---|---|---|
| MLH1 | c.688G>T p.(Glu230*) | 53 | M | Diffuse | T2N0 |
| MSH2 | c.(?_-68)_(*272_?)del p.(?) | 73 | F | Intestinal HP+ | T2N1 |
| MSH2 | c.2334C>A p.(Cys778*) | 62 | M | Intestinal HP+ | T2N0 |
| MSH2 | c.(?_-68)_1276+?del p.(?) | 40 | F | Intestinal HP+ | T2N1 |
| APC | c.1863-1866del p. (Thr621fs*8) | 54 | M | adenoma | |
| APC | c.1495C>T p.(Arg499*) | 72 | F | Krukenberg | T3N3 |
