Fig. 4.

Diurnal rhythm of mean arterial pressure (MAP). Cosinor regression analysis of 24-h MAP at baseline (protocol day −1, A) and after treatment (protocol day 14, B) was employed to assess the effects of treatment on MAP diurnal rhythm. Hourly averages of MAP are presented as means ± SE and fit with a cosinor regression curve. Cosinor regression analysis data are presented in Table 2. TRDNx, total renal denervation; ARDNx, afferent-selective renal denervation. Sham: n = 14; TRDNx: n = 16; ARDNx: n = 16.