Skip to main content
. 2018 Mar 7;314(6):R883–R891. doi: 10.1152/ajpregu.00416.2017

Fig. 5.

Fig. 5.

Neurogenic pressor activity. Measured by recording the acute depressor response to ganglionic blockade (30 mg/kg hexamethonium bromide), neurogenic pressure activity was measured before and 14 days after denervation treatment. TRDNx, total renal denervation; ARDNx, afferent-selective renal denervation. Pressor activity was similar across all groups at baseline (Sham −84 ± 7 vs. TRDNx −81 ± 5 vs. ARDNx −83 ± 7 mmHg). After treatment (2 wk), pressor activity was reduced in TRDNx and ARDNx compared with the time-matched Sham group and their respective baseline values [Sham −85 ± 6 vs. TRDNx −49 ± 4 (P < 0.05) vs. ARDNx −53 ± 2 mmHg (P < 0.05)]. Data are presented as means ± SE. *P < .05 vs. time-matched Sham; one-way ANOVA with Bonferroni post hoc test. Sham: n = 14; TRDNx: n = 16; ARDNx: n = 16.