Table 2.

Mean arterial pressure cosinor regression analysis

Cosinor Regression Statistic	Sham (n = 14)	TRDNx (n = 16)	ARDNx (n = 16)
Protocol day −1
MESOR, mmHg	157.0 ± 0.9	162.3 ± 0.8	156.9 ± 0.8
Amplitude, mmHg	11.4 ± 1.3	10.7 ± 0.9	9.7 ± 1.1
Acrophase, h	19.3 ± 0.3	19.8 ± 0.6	19.3 ± 0.3
Protocol day 14
MESOR, mmHg	154.4 ± 0.8	141.4 ± 0.6*	144.0 ± 0.6*
Amplitude, mmHg	13.6 ± 1.1	6.3 ± 0.9*	7.0 ± 0.8*
Acrophase, h	20.5 ± 0.6	20.2 ± 0.4	21.7 ± 0.5

Data are presented at means ± SE; n, no. of rats. MESOR, amplitude of day/night cycle, and acrophase were derived from hourly averages of 24-h recordings of mean arterial pressure at baseline (protocol day −1) 2 wk after treatment (protocol day 14).

^*P < 0.05 vs. time-matched Sham; one-way ANOVA with Bonferroni post hoc test.