Fig. 1.

Fetal plasma cortisol. Data are mean (±SE) daily concentrations of plasma cortisol for the 5 days during and after infusion of fetal sheep with either cortisol (n = 14–24 on days 0–5; n = 8–12 on days 6–10) or saline (n = 7–23 on days 0–5; n = 5–16 on days 6–10). The effects of study day (PDay), cortisol infusion (PCort), and the interaction of the 2 (PInter) were determined by two-way ANOVA. *P < 0.05 vs. corresponding saline-infused value by least significant difference post hoc test. The period of infusion is indicated by gray shading. Metabolic and biometric data were collected from subsets of animals on days 5 (during infusion) and 10 of the study period (+5 days after infusion was ended), as indicated by arrows.