Table 4.
Blood oxygen contents and oxygen uptakes on the final day of saline or cortisol infusion or 5 days thereafter
| During Infusion |
+5 Days Postinfusion |
P Value (Two-Way ANOVA) |
|||||
|---|---|---|---|---|---|---|---|
| Saline (n = 15) | Cortisol (n = 9) | Saline (n = 10) | Cortisol (n = 9) | Cortisol | Study day | Interaction | |
| Fetal arterial blood gas status | |||||||
| pH | 7.36 ± 0.01 | 7.34 ± 0.01 | 7.36 ± 0.01 | 7.33 ± 0.02 | 0.03 | 0.68 | 0.52 |
| Po2, mmHg | 18.6 ± 0.7 | 18.0 ± 1.2 | 20.4 ± 1.1 | 18.2 ± 1.1 | 0.16 | 0.33 | 0.40 |
| Pco2, mmHg | 52.0 ± 0.9 | 54.3 ± 0.8 | 52.1 ± 1.6 | 61.5 ± 4.0* | 0.01 | 0.09 | 0.09 |
| Hemoglobin, mg/dl | 9.7 ± 0.4 | 9.6 ± 0.4 | 10.6 ± 0.4 | 10.3 ± 0.4 | 0.59 | 0.07 | 0.76 |
| Hemoglobin saturation, % | 52.9 ± 2.1 | 48.2 ± 4.8 | 51.9 ± 2.7 | 44.3 ± 3.8 | 0.07 | 0.47 | 0.66 |
| Arterial blood O2 content, mM | |||||||
| Maternal | 5.2 ± 0.2 | 5.2 ± 0.2 | 5.0 ± 0.2 | 5.4 ± 0.3 | 0.35 | 0.93 | 0.45 |
| Fetal | 3.2 ± 0.2 | 2.8 ± 0.2 | 3.4 ± 0.2 | 2.8 ± 0.3 | 0.03 | 0.57 | 0.76 |
| Uterine O2 uptake, mmol/min | 1,676 ± 244 | 1,667 ± 138 | 1,560 ± 171 | 1,977 ± 164 | 0.34 | 0.65 | 0.32 |
| O2 consumption | |||||||
| Fetal, µmol/min | 892 ± 46 | 943 ± 53 | 995 ± 96 | 1,107 ± 76 | 0.24 | 0.06 | 0.66 |
| Fetal, µmol·min−1·kg fetus−1 | 305 ± 15 | 315 ± 20 | 281 ± 20 | 328 ± 29 | 0.18 | 0.79 | 0.38 |
| Uteroplacental, µmol/min | 859 ± 216 | 724 ± 153 | 564 ± 122 | 870 ± 159 | 0.64 | 0.69 | 0.24 |
| Uteroplacental, µmol·min−1 kg·placenta−1 | 2,845 ± 691 | 2,276 ± 427 | 2,039 ± 401 | 2,766 ± 512 | 0.89 | 0.79 | 0.27 |
Values are means ± SE.
P < 0.05 vs. saline, least significant difference post hoc test. Bold values significant effect by two-way ANOVA.