Table 5.
Blood lactate concentrations and uptakes on the final day of saline or cortisol infusion or 5 days thereafter
During Infusion |
+5 Days Postinfusion |
P Value (two-way ANOVA) |
|||||
---|---|---|---|---|---|---|---|
Saline (n = 15) | Cortisol (n = 9) | Saline (n = 9) | Cortisol (n = 9) | Cortisol | Study day | Interaction | |
Arterial blood lactate, mM | |||||||
Maternal | 0.48 ± 0.06 | 0.45 ± 0.03 | 0.55 ± 0.04 | 0.45 ± 0.04 | 0.20 | 0.57 | 0.49 |
Fetal | 1.21 ± 0.09 | 1.58 ± 0.16 | 1.58 ± 0.16 | 1.22 ± 0.18 | 0.97 | 0.98 | 0.01 |
Uterine lactate uptake, µmol/min | 43 ± 5 | 43 ± 7 | 64 ± 22 | 69 ± 18 | 0.84 | 0.08 | 0.84 |
Umbilical lactate uptake, µmol/min | 52 ± 12 | 81 ± 17 | 85 ± 22 | 89 ± 13 | 0.30 | 0.21 | 0.41 |
Umbilical lactate uptake, µmol·min−1·kg fetus−1 | 17 ± 4 | 27 ± 5 | 24 ± 5 | 25 ± 4 | 0.22 | 0.62 | 0.39 |
Uteroplacental lactate production, µmol/min | 94 ± 13 | 124 ± 15 | 149 ± 33 | 158 ± 22 | 0.36 | 0.04 | 0.61 |
Uteroplacental lactate production, µmol·min−1·kg placenta−1 | 318 ± 44 | 428 ± 60 | 564 ± 142 | 504 ± 55 | 0.76 | 0.05 | 0.29 |
Values are means ± SE. Boldface values indicate significant effect by two-way ANOVA.