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. 2018 May 24;19(6):1567. doi: 10.3390/ijms19061567

Figure 1.

Figure 1

Figure 1

Luteolin inhibits LX-2 and HSC-T6 cell proliferation. (a) LX-2 and HSC-6 cell viability after treatment with a series of concentrations of luteolin for 48 h (left panel). LX-2 (middle panel) and HSC-T6 (right panel) cell viability after treatment with vehicle or 40 µM of luteolin for 24, 48, or 72 h; (b) Percent of cells in G1 and S phase after treatment with vehicle or 40 µM of luteolin for 24 h; (c) Western blots with LX-2 whole cell lysate after incubation with vehicle or 40 µM of luteolin for 24 h for cell cycle regulatory proteins cyclin-dependent kinase 9 (CDK9), cyclin B1 and minichromosome maintenance protein 2 (MCM2). p-Values shown compared to vehicle. The results are representative of at least 3 independent experiments. All summary bar and line graphs are presented as mean ± SEM, with significance denoted as follows *: p < 0.05, **: p < 0.01, ***: p < 0.001.