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Schematic representation of the multi-cistronic operons containing the major heat-shock proteins of H. pylori. The HspR regulator represses alone the transcription of its own cbpA-hspR-orf operon, while both HspR and HrcA repressors combine to control the expression of groEL-groES and hrcA-grpE-dnaK operons. HspR and HrcA DNA-binding and transcriptional repression are represented by solid and dotted lines, respectively.
