Table 3.
Compound | IC50/µM 1 | |
---|---|---|
HT-29 | MCF-7 | |
ASA | ≥50 | ≥50 |
Zeise’s salt | ≥50 | ≥50 |
1a | 49.7 ± 1.8 | ≥50 |
2a | 31.4 ± 0.4 | 30.1 ± 1.5 |
3a | 44.2 ± 3.4 | 37.4 ± 2.5 |
4a | 41.4 ± 0.3 | 43.7 ± 5.7 |
Cisplatin | 2.6 ± 0.1 | 3.7 ± 0.3 |
1 IC50 values represent the concentration where 50% of the compounds maximum antiproliferative activity compared to vehicle treated control was achieved. Results are given as mean ± standard error of mean of ≥2 independent experiments.