Table 1.
Univariate and multivariate Cox regression analyses to identify predictors of overall survival in ccRCC and papillary RCC (pRCC).
| Variable | Group | Unadjusted HR (95% CI) | p Value | Adjusted HR (95% CI) | p Value |
|---|---|---|---|---|---|
| KIRC (n = 533) | |||||
| Age (per year) | 1.02 (1.02–1.04) | <0.0001 | - | - | |
| Sex | Male | 0.95 (0.69–1.31) | 0.77 | - | - |
| Female | 1 | ||||
| Stage | High (stage III–IV) | 4.28 (3.06–5.99) | <0.0001 | - | - |
| Low (stage I–II) | 1 | ||||
| Distant metastasis | M1 | 4.59 (3.32–6.33) | <0.0001 | - | - |
| M0 | 1 | ||||
| Fuhrman grade | High (Gr 3–4) | 2.85 (1.98–4.11) | <0.0001 | - | - |
| Low (Gr 1–2) | 1 | ||||
| Prediction score | Low (<−1.925) | 4.53 (3.05–6.73) | <0.0001 | 2.68 (1.75–4.11) | <0.0001 |
| High (≥−1.925) | 1 | ||||
| KIRP (n = 287) | |||||
| Age (per year) | 1.01 (0.98–1.04) | 0.56 | - | - | |
| Sex | Male | 0.72 (0.32–1.62) | 0.43 | - | - |
| Female | 1 | ||||
| Stage | High (stage (III–IV) | 4.86 (2.22–10.66) | <0.0001 | - | - |
| Low (stage I–II) | 1 | ||||
| Prediction score | Low (<−1.723) | 13.19 (6.03–28.83) | <0.0001 | 7.44 (3.01–18.41) | <0.0001 |
| High (≥−1.723) | 1 |
HR: Hazard ratio.