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. 2018 Jul 5;13(4-5):255–269. doi: 10.3727/000000006780666948

TABLE 1.

ZOXAZOLAMINE PARALYSIS TEST

PRIP+/+ PRIPLiv−/−
Control 4/13: 2-h paralysis; recovered 1/11: 2-h paralysis; recovered
5/13: 3-h paralysis; recovered 6/11: 3-h paralysis; recovered
1/13: 4-h paralysis; recovered 1/11: 4-h paralysis; dead
1/13: 6-h paralysis; recovered 1/11: 8-h paralysis; dead
1/13: 6-h paralysis; dead 2/11: 12-h paralysis; recovered
1/13: 9-h paralysis; dead
PB (3 days) 8/8: not paralyzed 8/8: not paralyzed

Control and 3-day PB-treated male mice (5–6 weeks old) were given a single IP injection of zoxazolamine (300 mg/kg of body weight), and paralysis duration was recorded as the time when the mice were able to right themselves repeatedly. Very similar results were observed in both wild-type (PRIP+/+) and knockout (PRIP−/−) mouse groups.