Table 1.
Prebiopsy characteristics of case and control patients
| Characteristic | Kidney AA amyloidosis, n=38 | Complete Data | Other Kidney Diagnoses, n=72 | Complete Data |
|---|---|---|---|---|
| Agea | 45±9 | 38 | 46±10 | 72 |
| Womena | 12 (32) | 38 | 23 (32) | 72 |
| Racea | 38 | 72 | ||
| White | 28 (74) | 52 (72) | ||
| Black | 5 (13) | 7 (10) | ||
| Other | 5 (13) | 13 (18) | ||
| Smoking status | 38 | 72 | ||
| Never | 4 (11) | 40 (56) | ||
| Former | 2 (5) | 8 (11) | ||
| Current | 32 (84) | 24 (33) | ||
| Body mass index, kg/m2 | 27±8 | 37 | 28±6 | 68 |
| Past medical history | 38 | 72 | ||
| Diabetes | 2 (5) | 13 (18) | ||
| Cirrhosis | 1 (3) | 3 (4) | ||
| Rheumatoid arthritis | 1 (3) | 1 (1) | ||
| Tuberculosis | 6 (16) | 4 (6) | ||
| Inflammatory bowel disease | 1 (3) | 2 (3) | ||
| Lupus | 2 (5) | 15 (21) | ||
| Sjogren syndrome | 0 (0) | 1 (1) | ||
| eGFR, ml/min per 1.73 m2 | 38±30 | 38 | 48±32 | 71 |
| Serum albumin, g/dl | 1.8±0.8 | 36 | 3.0±0.8 | 68 |
| Serum HDL cholesterol, mg/dl | 30±21 | 25 | 48±23 | 45 |
| Serum triglycerides, mg/dl | 210±101 | 25 | 167±131 | 47 |
| HIV | 4 (11) | 36 | 14 (22) | 65 |
| Hepatitis B core antibody | 5 (26) | 19 | 11 (28) | 39 |
| Hepatitis C antibody | 14 (74) | 19 | 10 (24) | 42 |
| Proteinuria, g/d or g/gb | 12 (5, 15) | 30 | 3 (1, 6) | 48 |
| Kidney size, cmc | 12.8±1.6 | 33 | 11.3±1.3 | 56 |
All values are expressed as mean±SD or number (percentage of nonmissing values), except for urine protein, which is expressed as median (interquartile range).
a
Matching characteristics.
b
Urine protein expressed as grams per 24 hours if timed data were available, or g/g from spot collection.
c
Average of right and left kidney sizes.