Table 4.
Patterns of illicit drug use, related medical conditions, and risk of kidney AA amyloidosis
| Characteristic | Complete Data | Kidney AA Amyloidosis, n=38 | Other Kidney Diagnosis, n=72 | Odds Ratioa (95% Confidence Interval) |
|---|---|---|---|---|
| Any heroin use | 108 | 35 (95) | 10 (14) | 169.5 (28.2 to 1018.2)b |
| Recent use | 107 | 28 (78) | 2 (3) | 222.6 (37.5 to 1322.8)b |
| Intravenous use | 108 | 30 (81) | 9 (13) | 37.0 (11.0 to 124.8)b |
| Muscling | 108 | 28 (76) | 0 (0) | — |
| Skin popping | 108 | 10 (27) | 0 (0) | — |
| Cocaine use | 110 | 29 (76) | 14 (19) | 26.0 (7.5 to 89.9)b |
| Methamphetamine use | 109 | 7 (18) | 5 (7) | 3.4 (0.9 to 12.5) |
| Skin abscess | 110 | 33 (87) | 8 (11) | 64.7 (16.6 to 252.7)b |
| Endocarditis | 110 | 5 (13) | 2 (3) | 6.9 (1.0 to 45.5)c |
| Bacteremia | 110 | 28 (74) | 13 (18) | 20.0 (6.2 to 64.5)b |
All values are expressed as number (percentage of nonmissing values). —, not applicable.
a
Odds ratios adjusted for matching variables: age, race, sex, site, and calendar year of biopsy.
b
P value<0.001.
c
P value=0.05.