Table 2.
Pairwise comparison between samples obtained from the same subject at the time of initial infection and at the time of recurrent parasitemia
| Initial infection | Recurrent parasitemia | Segregating sites | Core genome identical by descent (%) | Microsatellites (concordant/typed) |
|---|---|---|---|---|
| PQPC-029-0 | PQPC-029-84 | 137 | 98.6 | 6/6 |
| PQPC-035-0 | PQPC-035-83 | 561 | 4.6 | 3/6 |
| PQPC-047-0 | PQPC-047-43 | 566 | 5.6 | 1/6 |
| PQPC-071-0 | PQPC-071-105 | 560 | 6.8 | 1/6 |
| PQPC-088-0 | PQPC-088-91 | 272 | 98.1 | 5/6 |
| PQPC-113-0 | PQPC-113-76 | 72 | 99.3 | 6/6 |
| PQPC-117-0 | PQPC-117-52 | 385 | 2.3 | 1/4 |
| PQPC-125-0 | PQPC-125-80 | 134 | 98.7 | 6/6 |
| PQPC-128-0 | PQPC-128-87 | 392 | 98.1 | 6/6 |
| PQPC-135-0 | PQPC-135-120 | 262 | 99.3 | 6/6 |
| PQPC-139-0 | PQPC-139-121 | 111 | 99.3 | 2/3 |
| PQSC-013-0 | PQSC-013-52 | 337 | 9.7 | 2/6 |
| PQSC-042-0 | PQSC-042-134 | 347 | 52.0 | 2/6 |
| PQSC-058-0 | PQSC-058-30 | 66 | 99.4 | 6/6 |
| PQSC-105-0 | PQSC-105-32 | 381 | 25.8 | 6/6 |
| PQSJ-058-0 | PQSJ-058-40 | 516 | 8.2 | 2/6 |
| PQSJ-122-0 | PQSJ-122-144 | 61 | 100 | 0/6 |
| PQSJ-171-0 | PQSJ-171-129 | 218 | 99.3 | 6/6 |
| PQSJ-190-0 | PQSJ-190-98 | 117 | 99.7 | 5/6 |
| PQSJ-199-0 | PQSJ-199-56 | 559 | 41.2 | 4/6 |
| PQSJ-202-0 | PQSJ-202-100 | 269 | 99.0 | 6/6 |
| PQSJ-284-0 | PQSJ-284-71 | 171 | 99.4 | 6/6 |
| PQSJ-294-0 | PQSJ-294-73 | 200 | 100 | 6/6 |
The mean number of segregating sites for all 69 samples included in the study was 489. We identified 12 pairs that are most likely to be homologous relapses, based on the mean number of segregating sites minus 1.5 standard deviations (< 290) and core genome IBD ≥ 99%, which are italicized