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. 2018 Mar 30;93(7):1901–1915. doi: 10.1002/jctb.5599

Figure 1.

JCTB-5599-FIG-0001-c

Scheme for the manufacture of the 4‐MEP linked magnetic supports used in this study. Key: a i NaOH, rt; a ii washing (water → NaCl → methanol), rt; b i 3‐aminopropyltriethoxysilane, glacial acetic acid, methanol, 600 s @ 13 000 rpm → 2 h @ 6000 rpm, rt; b ii glycerol, N2, 11 h @ 110 °C, 0.5 h @ 160 °C; b iii washing (water → NaCl → water), rt; c i glutaraldehyde, pH 11, 1 h, rt; c ii washing (water → NaCl → water); d epichlorohydrin, NaOH, NaBH4, 6 h, rt; e allyl bromide, NaOH, NaBH4, DMSO, 18–20 h, rt; f allyl glycidyl ether, NaOH, NaBH4, DMSO, 18–20 h, rt; g divinylsulphone, Na2CO3, 1 h, rt; h N‐bromosuccinimide, 1 h, rt; j 4‐mercaptoethyl pyridine hydrochloride, Na2CO3, NaBH4, 48 h, rt.