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. 2018 Apr 1;104(1):159–171. doi: 10.1002/JLB.3MA1017-404R

Figure 8.

Figure 8

DP1 receptor agonist BW245c enhances (A) mRNA expression of CCR3 and VLA‐4 and (B) upregulates surface expression of CCR3 and VLA‐4. Isolated eosinophils (5 × 106/ml) were incubated with vehicle (EtOH), DK‐PGD2 [1 μM], or BW245c [1 μM] for 3 h (A) or 18h (B) (RPMI, 1% FBS, 1%, PenStrep, 37°C). mRNA expression was measures by qRT PCR (A). Surface expression was determined by flow cytometric analysis (B). Data show mean ± sem (n = 5–10)