Table 1.
DaxibotulinumtoxinA dose | |||
---|---|---|---|
100–240 U (N = 21) |
300–450 U (N = 16) a |
100–450 U (N = 37) (Combined group) |
|
Mean age ± SD, yrs | 54 ± 10.4 | 58 ± 10.6 | 56 ± 10.4 |
[range] | [32–74] | [30–70] | [30–74] |
Females, n (%) | 18 (86%) | 10 (63%) | 28 (76%) |
Caucasians, n (%) | 18 (86%) | 14 (88%) | 32 (86%) |
Duration of cervical dystonia, yrs | |||
Mean ± SD | 7.3 ± 8.09 | 7.9 ± 7.13 | 7.6 ± 7.59 |
Median [range] | 4.8 [0.0–24.1] | 7.2 [0.0–23.3] | 4.9 [0.0–24.1] |
Prior treatment with botulinum toxin, n | 9 (43%) | 8 (50%) | 17 (46%) |
Mean dose of daxibotulinumtoxinA ± SD, U | 188 ± 35.1 | 319 ± 39.3 | 244 ± 75.4 |
Mean TWSTRS score ± SD | |||
Total score | 44.4 ± 9.52 | 43.8 ± 10.20 | 44.1 ± 9.69 |
Severity subscore | 20.5 ± 3.23 | 21.9 ± 3.89 | 21.1 ± 3.55 |
Disability subscore | 12.6 ± 3.92 | 11.6 ± 4.51 | 12.2 ± 4.15 |
Pain subscore | 11.3 ± 4.63 | 10.3 ± 4.55 | 10.8 ± 4.56 |
CDIP‐58 total score | |||
Mean ± SD | 53.9 ± 18.76 | 49.7 ± 14.90 | 52.1 ± 17.10 |
Median [range] | 51.4 [22.8–90.7] | 55.9 [23.5–71.7] | 54.8 [22.8–90.7] |
Abbreviations: CDIP‐58, Cervical Dystonia Impact Profile; SD, standard deviation; TWSTRS, Toronto Western Spasmodic Torticollis Rating Scale
aThree were reenrolled from lower‐dose group.