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. Author manuscript; available in PMC: 2018 Jul 5.
Published in final edited form as: Cell Rep. 2018 May 1;23(5):1553–1564. doi: 10.1016/j.celrep.2018.03.133

Figure 2. IDH1R132H Cooperates with PDGFA and Loss of Cdkn2a, Atrx, and Pten to Promote Glioma Formation In Vivo.

Figure 2

(A) Kaplan-Meier tumor-free survival analysis of N::TVA;Cdkn2alox/lox;Atrxlox/lox;Ptenlox/lox mice infected with viruses containing PDGFA and Cre (n = 15, dotted line), PDGFA, Cre, and IDH1 (n = 15, dashed line), or PDGFA, Cre, and IDH1R132H (n = 16, solid line).

(B) Kaplan-Meier tumor-free survival analysis of the mouse strains indicated infected with viruses containing PDGFA, Cre, and IDH1R132H.

Statistical significance is denoted by ***p < 0.001. ns, not significant. See also Figure S2 and Tables S1 and S2.