Table 1.
Demographic and Clinical Data
| Variable |
PD, RBD+ (n = 33) |
PD, RBD – (n = 101) |
p‐value PD RBD+ vs. PD RBD‐ |
iRBD (n = 30) |
CTR (n = 107) |
p‐value iRBD vs. CTR |
|---|---|---|---|---|---|---|
| Age (mean +/− SD) | 66 +/− 8.2 | 64 +/− 10.2 | 0.18 | 65 +/− 11.2 | 65 +/− 6.9 | 0.93 |
| Sex male (%) | 22 (67%) | 66 (65%) | 0.89 | 18 (60%) | 64 (60%) | 0.96 |
| PD duration in months median (IQR) | 12 (8–24) | 17 (12–24) | 0.36 | n.a. | n.a. | n.a. |
| MDS‐UPDRS score median (IQR) | 35 (24–47.5) | 34 (23–48.5) | 0.8 | 17 (13–25) | 2 (1–5) | 0.00 |
| RBDSQ score median (IQR) | 4.2 (2.2–8) | 2.4 (1.1–4.3) | 0.003 | 9 (7–11) | 2 (1–4) | 0.00 |
|
PDSS‐2 question 6 score median (IQR) mean +/− SD |
1 (0–2) 0.97 +/− 1.16 |
0 (0–1) 0.68 +/− 0.98 |
0.19 0.20 |
1 (0–2.25) 1.30 +/− 1.37 |
0 (0–1) 0.50 +/− 0.75 |
0.002 0.004 |
Abbreviations: PD, Parkinson's disease; RBD, REM sleep behavior disorder; CTR, controls; iRBD, idiopathic RBD patients; IQR, interquartile range; MDS‐UPDRS, Movement Disorder Society‐Unified Parkinson's Disease Rating Scale; RBDSQ, RBD screening questionnaire; PDSS, Parkinson's Disease Sleep Scale.